API / Alfa Chemistry

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Tofacitinib citrate

Catalog Number
MC540737299
CAS
540737-29-9
Structure
Synonyms
(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile; 2-Hydroxy-1,2,3-propanetricarboxylate
Molecular Weight
504.4986
Molecular Formula
C22H28N6O8
Melting Point
198-200°C
Purity
96%
Physical State
Solid
Standard
CP
Description
Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.
Spec Sheet
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